| | Position | | Title, Artist | Video |
|---|
 | 1Last Week: 2 |  |
Ian Carey, Michelle ShellersKeep On Rising (ManyFew, Joe Stone Extended Remix) |
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| 2Last Week: 3 |  |
Crazibiza, Laurent SimecaAin't No Sunshine (Original Mix) |
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| 3Last Week: 6 |  |
Pet Shop BoysWest End Girls (New Lockdown Version) |
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| 4Last Week: 9 |  |
KungsNever Going Home |
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| 5Last Week: 13 |  |
JoanneTwist In My Sobriety |
|
 | 6Last Week: 1 |  |
Stylo, Space MotionYeke Yeke |
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| 7Last Week: 16 |  |
Maceo Plex, FaithlessInsomnia 2021 (Epic Mix) |
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| 8Last Week: 4 |  |
Block & CrownLet It Play (On & On NuDisco 2021 Mix) |
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| 9Last Week: 5 |  |
Leo SayerEasy To Love (Dimitri From Paris Remix) |
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| 10Last Week: 27 |  |
Diplo, SidepieceOn My Mind (Purple Disco Machine Extended Remix) |
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| 11Last Week: 31 |  |
TiestoThe Business (Sparkee Remix) |
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| 12Last Week: 23 |  |
MobyGo (Reprise Version) |
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| 13Last Week: 7 |  |
Ali Bakgor, Kallay SaundersOcean |
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| 14Last Week: 19 |  |
Nelly Furtado, QuarterheadAll Good Things (Come To An End) (Extended Remix) |
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| 15Last Week: 8 |  |
Luigi CatalanoMa Quale Idea (Buscemi Remix) |
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| 16Last Week: 24 |  |
Yotto, Sansa, CristophOut Of Reach (Club Mix) |
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| 17Last Week: 11 |  |
MinelliRampampam |
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| 18Last Week: 35 |  |
Calvin Harris, Tom GrennanBy Your Side (Original Mix) |
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| 19Last Week: 10 |  |
Dennis Ferrer, Tyrone EllisUnderground Is My Home (Crazibiza Remix) |
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| 20Last Week: 32 |  |
Haze-MPump Up The Jam (Original Mix) |
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| 21Last Week: 14 |  |
MarkosaJosephine 2021 (Soul Avengerz Mix) |
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| 22Last Week: 12 |  |
Black Box, Loleatta HollowayRide On Time (79 Disco Anthem) |
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| 23Last Week: 38 |  |
Master KG, David Guetta, AkonShine Your Light |
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| 24Last Week: 51 |  |
DirtytwoStay |
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| 25Last Week: 44 |  |
Lost FrequenciesRise (Twocolors Extended Remix) |
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| 26Last Week: 36 |  |
David Penn, Ramona ReneaLift Your Hands Up (Extended Mix) |
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| 27Last Week: 57 |  |
Stylo, Space MotionPlayer (Original Mix) |
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| 28Last Week: 61 |  |
Alok, Glimmer Of BloomsMy Head (Can’t Get You Out) (Extended Mix) |
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| 29Last Week: 46 |  |
Elektrik DiskoTell Me Why (Extended Mix) |
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| 30Last Week: 15 |  |
Dennis Cruz, Josh ButlerAhora Todo Va (Original Mix) |
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| 31Last Week: 68 |  |
Zibadan, Nicola Corradino, Karmina DaiLast Night A DJ Saved My Life (Trip Mix) |
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| 32Last Week: 17 |  |
Glovibes, Lana ParrillaIt's Over Now (Original Mix) |
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| 33Last Week: 58 |  |
Ofenbach, LagiqueWasted Love (James Hype Extended Remix) |
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| 34Last Week: 18 |  |
Milk Bar, Antonio ContinoNew Orleans (Extended Mix) |
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| 35Last Week: 55 |  |
Freedom Dub, Rosin TaylorLight My Fire |
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| 36Last Week: 59 |  |
La RouxBulletproof (Gamper & Dadoni Remix) |
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| 37Last Week: 64 |  |
Paul Parsons, LissatSexy (Original Mix) |
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| 38Last Week: 20 |  |
Yann MullerEnglishman In New York (Original Mix) |
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| 39Last Week: 21 |  |
Black BoxI Don't Know Anybody Else (Motown Disco Anthem) |
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| 40Last Week: 22 |  |
Martin Garrix, Bono & The EdgeWe Are The People (Official UEFA Euro 2020 Song) |
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| 41Last Week: 80 |  |
Geraldine HuntCan't Fake The Feeling (Carl Cox Extended Rework) |
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| 42Last Week: 28 |  |
M&S, The Girl Next DoorSalsoul Nugget (If You Wanna) (Mark Knight Extended Remix) |
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| 43Last Week: 66 |  |
HypnomusicLights |
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| 44Last Week: 29 |  |
Waterstone, Tracy HamlinI Miss You (Original Mix) |
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| 45Last Week: 33 |  |
Stereo DubHeartbeats (Old Beats Mix) |
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| 46Last Week: 26 |  |
Sean FinnDisco Revenge 2021 (Extended Mix) |
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 | 47Last Week: -- |  |
Andrelli, ShirinSway (Extended Version) |
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| 48Last Week: -- |  |
Wh0I'm Coming (Extended Mix) |
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| 49Last Week: 75 |  |
NariThat's The Way (Original Mix) |
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| 50Last Week: 71 |  |
Sixth FingerAlone (City 48 Mix) |
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